Specifications: 0.2 g
Term of Validity: 3 years
Approval Number: GYZZ H42021947
Applicable Symptoms: This product is indicated for the treatment and prevention of infections identified or suspected to be caused by anaerobic bacteria. This product has inhibitory activities against a variety of pathogenic microorganisms, especially Bacteroides, Fusobacteria, Clostridium, Eubacteria, Peptococcus, Peptostreptococcus, Anaerococcus and Gardnerella vaginalis. It also has therapeutic effects against Trichomonas vaginalis, Entamoeba histolytica Schaudinn, Giardia lamblia, Balantidium coli and Dracunculus medinensis. The indications of this product for adults and children are as follows: 1. Anaerobic infection (1) For the prevention of postoperative anaerobic infections, especially the infections caused by Bacteroides and P. anaerobius (2) For the treatment of skin and soft tissue infections, bone and joint infections (as an adjuvant therapy), endocarditis, sepsis, bacteremia, peritonitis, abdominal abscess, liver abscess, meningitis, brain abscess, necrotizing pneumonia, empyema, lung abscess, osteomyelitis, puerperal cerebral toxemia, pelvic abscess, pelvic cellulitis, endometritis, endomyometritis, tubo-ovarian abscess, postoperative vaginal uterine infection, and postoperative wound infection where pathogenic anaerobic bacteria can be isolated or highly suspected concurrent anaerobic infection is present. (3) For the treatment of leg ulcers and pressure sores caused by anaerobic bacteria infections. 2. Trichomoniasis (1) For the treatment of female (trichomonas vaginitis, urethral trichomoniasis, etc.) and male patients with urogenital trichomoniasis. (2) For the treatment of asymptomatic sexual partners. 3. Bacterial vaginosis (also known as nonspecific vaginitis, anaerobic vaginitis or Gardnerella vaginitis). 4. Amoebiasis For the treatment of all forms of amoebiasis, including intestinal and parenteral amoebiasis (such as amebic liver abscess, pleural amoebiasis), as well as asymptomatic amoebiasis. 5. Oral infection (1) For the treatment of ulcerative gingivitis. (2) For the treatment of odontogenic infections (such as acute periodontitis and acute periapical periodontitis). 6. Giardiasis, balanomiasis, dermal leishmaniasis anddracunculiasis, etc. To reduce the production of drug-resistant bacteria and ensure the efficacy of metronidazole tablets and other antibacterial drugs, metronidazole tablets shall be limited to the treatment or prevention of infections that have been proved or are strongly suspected to be caused by bacteria. Official guidelines shall also be referred to for the rational use of antibacterial drugs.
Contact Number: 4009909697
Manufacturer: Grand Pharmaceutical (China) Co., Ltd.
Usage and Dosage: (1) For the prevention of postoperative anaerobic infection: mainly used in abdominal surgeries and obstetric and gynecological surgeries. Adults: 400 mg per os every 8 hours for 24 hours before surgery, followed by intravenous or rectal administration after surgery until the patient is able to take tablets orally. Children: Less than 12 years old: a single dose of 20-30 mg/kg, 1-2 hours before the surgery; Neonates with less than 40 weeks of gestation: a single dose of 10 mg/kg before the surgery. (2) Treatment of anaerobic infection: The course of treatment is about 7 days, which also depends on the severity of the patient's condition based on clinical and bacteriological evaluation. Adults: Initial dose of 800 mg, followed by a dose of 400 mg every 8 hours. Children: 8 weeks to 12 years old: routine daily dose is 20-30 mg/kg, which can be administered at a single time or at a single dose of 7.5 mg/kg every 8 hours. Depending on the severity of the infection, the daily dose can be increased to 40 mg/kg. The course of treatment is usually 7 days. Infants aged less than 8 weeks: Daily dose of 15 mg/kg, which can be administered at a single time or at a single dose of 7.5 mg/kg every 12 hours. In neonates with less than 40 weeks of gestation, accumulation of metronidazole may occur within the first week of birth. Therefore, it is strongly recommended to monitor the metronidazole concentration in serum following several days of treatment. (3) Leg ulcers and pressure sores: Adults or children over 10 years old: 400 mg tid for 7 days.
Applicable Symptoms: Indicated for heart failure caused by decreased myocardial contractility in organic heart disease, including low cardiac output syndrome after open heart surgery, as a short-term supportive therapy.
Applicable Symptoms: It is mainly indicated for severe dyspnea caused by bronchospasm. It can quickly relieve anaphylactic shock caused by drugs, and can also prolong the action time of infiltration anesthetics. It is the primary rescue drug in cardiopulmonary resuscitation for cardiac arrest caused by various reasons.
Applicable Symptoms: 1. It can help increasing blood pressure to treat hypotension during general anesthesia and prevent arrhythmia; and it can also be used to treat hypotension induced by intraspinal block, but with the possibility of reducing cardiac output. 2. It can be used to terminate the onset of paroxysmal supraventricular tachycardia.
Applicable Symptoms: Indicated for shock syndrome caused by myocardial infarction, trauma, endotoxin sepsis, cardiac surgery, renal failure, and congestive heart failure; and for shock events that cannot be rescued by blood volume supplementation, especially for those with oliguria and normal or low peripheral vascular resistance. Since this product can increase cardiac blood output, it is also used for cardiac insufficiency where foxglove and diuretics are ineffective.
Applicable Symptoms: It is mainly indicated for severe dyspnea caused by bronchospasm. It can quickly relieve anaphylactic shock caused by drugs, and can also prolong the action time of infiltration anesthetics. It is the primary rescue drug in cardiopulmonary resuscitation for cardiac arrest caused by various reasons.
Applicable Symptoms: Indicated for blood pressure control in certain acute hypotensive situations (e.g., pheochromocytoma resection, sympathectomy, poliomyelitis, spinal anesthesia, myocardial infarction, sepsis, blood transfusion, and drug adverse reactions). Used as an adjuvant therapy for cardiac arrest and severe hypotension. For the emergency treatment of hypovolemia-induced shock, this product can be used as an adjuvant therapy to achieve blood volume supplementation, so as to help increase blood pressure and temporarily maintain perfusion in cerebral and coronary arteries until the blood volume supplementation takes effect; it can also be used for maintaining blood pressure after cardiopulmonary resuscitation (CPR).
